GMA Antibodies

At Green Mountain Antibodies, our product line focus is on the antigen. Listed below are the antigens to which we have developed and characterized antibodies. Please click on the antigen of interest to view a detailed specification sheet and any related antibodies which we stock.
Coagulation
Factor V
Factor VIIa

Factor VIII

Factor IX
Factor X
Factor XI
Factor XII
Factor XIII
Protein C
Prothrombin
Thrombin
Tissue Factor
Fibrinolysis
Angiostatin/Plasminogen
Fibrinogen
Tissue Plasminogen Activator
Other Blood Antibodies
Antithrombin
C4b-Binding Protein
Glutathione S-Transferase
Vitronectin
von Willebrand Factor

Product Detail

 

Anti-Plasminogen/Angiostatin

Clone GMA-086

 

 

Epitope:  Kringle 4 segment of plasminogen

 

Immunogen:  Human plasminogen

 

Host:  Murine

 

Clonality:  Monoclonal

 

Hybridoma:  NS-1 x murine spleen cells (Balb/c)

 

Isotype:  IgG1

 

Specificity & Applications: 

Solid-phase ELISA:  Antibody binds recombinant human plasminogen and angiostatin, specifically kringle 4, in solid-phase and solution-phase ELISA.  Antibody binds only slightly to isolated plasminogen kringle fragment 1-4 and does not bind isolated fragment 1-3.

 

Immunoblotting:  

Antibody binds human plasminogen, approximate molecular weight of 88 kD, and recombinant angiostatin under reduced and non-reduced conditions.

Product Form:  Lyophilized from a 1 mg/ml solution with 10 mM NaH2PO4, 0.15 M NaCl, 1.0% mannitol, pH 7.4.  Concentration determined by absorbance measurement at 280 nm and using an extinction coefficient of 1.4 (E0.1%).

 

Purity:  Confirmed >98% pure by SDS-PAGE

 

Working Concentration:  Approximately 1-5 μg/ml.  Researcher should titer antibody in specific assay.

 

Country of Origin:  USA


GMA-086 - Anti-Human Plasminogen/Angiostatin. Kringle 4 (Clone GMA-086)

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